Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29042545 | 0.87 | MEN1 (0.56) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL15264825 | 0.84 | MEN1 (0.53) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL126110 | 0.81 | MAPT (0.61) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL718255 | 0.80 | MAPT (0.74) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL29198018 | 0.80 | CYP1A2 (0.39) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL496226 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL11691634 | 0.79 | MAPT (0.64) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL669313 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL5964901 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2AL3MBTL1POLB | |
| Methane SCHEMBL9392239 | 0.78 | MAPT (0.57) | MAPTMEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1189447-C | Process for synthesizing 6-18F-L-dopa | NANFANG HOSPITAL (CN) | 2005-02-16 | — | — | CN | claimed |
| CN-1408705-A | Process for synthesizing 6-18F-L-dopa | NANFANG HOSPITAL (CN) | 2003-04-09 | — | — | CN | claimed |
| CN-104651476-A | Novel nitroreductase enzymatic substrates | BIOMERIEUX SA | 2015-05-27 | — | — | CN | disclosed |
| CN-104531832-A | Novel nitroreductase enzymatic substrates | BIOMERIEUX SA | 2015-04-22 | — | — | CN | disclosed |
| CN-102124123-B | Novel Nitroreductase Substrates | BIOMERIEUX SA | 2015-01-14 | — | — | CN | disclosed |
| CN-104262073-A | Small modular multifunctional automatic 18F labelling PET (positron emission tomography) drug synthesizer | BEIJING SHANWEIZHENGZI MEDICAL TECHNOLOGY CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-102016061-B | Novel peptidase substrates | BIOMERIEUX SA | 2014-09-24 | — | — | CN | disclosed |
| CN-101111483-B | IGF-1R inhibitors | KYOWA HAKKO KIRIN CO.,LTD. (JP) | 2011-12-14 | — | — | CN | disclosed |
| CN-102124123-A | Novel Nitroreductase Substrates | BIOMERIEUX SA | 2011-07-13 | — | — | CN | disclosed |
| CN-102016061-A | Novel peptidase substrates | BIOMERIEUX SA | 2011-04-13 | — | — | CN | disclosed |
| CN-101679034-A | The method for preparing active [18] F fluorochemical | TRASIS S A | 2010-03-24 | — | — | CN | disclosed |
| CN-1950341-A | Naphthalimide derivatives for the treatment of cancer | UNIBIOSCREEN SA (BE) | 2007-04-18 | — | — | CN | disclosed |
| CN-1189447-C | Process for synthesizing 6-18F-L-dopa | NANFANG HOSPITAL (CN) | 2005-02-16 | — | — | CN | disclosed |
| CN-1408705-A | Process for synthesizing 6-18F-L-dopa | NANFANG HOSPITAL (CN) | 2003-04-09 | — | — | CN | disclosed |
| CN-1092188-C | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHON NOHYAKU CO LTD (JP) | 2002-10-09 | — | — | CN | disclosed |
| CN-1134933-A | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHON NOHYAKU CO LTD (JP) | 1996-11-06 | — | — | CN | disclosed |
| CN-87108011-A | New compounds with pharmacological activity, preparation method and related components thereof | ORION YHTYMAE OY (FI) | 1988-06-08 | — | — | CN | disclosed |
| CN-86101879-A | Herbicidal heterocyclic | — | 1987-04-08 | — | — | CN | disclosed |
| US-4454337-A | Semicarbazide intermediates for preparing 4-substituted indoles | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4394514-A | Processes for preparing 4-substituted indoles | SMITHKLINE BECKMAN CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |