Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28882606 | 0.93 | MAPT (0.50) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL155768 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL155769 | 0.81 | ALDH1A1 (0.55) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL18173523 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL11047720 | 0.80 | MAPT (0.56) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL3364326 | 0.79 | MAPT (0.51) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL496224 | 0.79 | MAPT (0.51) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL3121631 | 0.78 | MEN1 (0.48) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL26876840 | 0.78 | ALDH1A1 (0.51) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL3361206 | 0.78 | MAPT (0.50) | MAPTMEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744101-A | Photolabile nucleoside protecting groups | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-28 | — | — | US | claimed |
| US-5451683-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. | 1995-09-19 | — | — | US | claimed |
| US-5252743-A | Using cage binding compound | AFFYMAX TECHNOLOGIES N.V. (NL) | 1993-10-12 | — | — | US | claimed |
| EP-0502060-A4 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | — | 1993-05-05 | — | — | EP | claimed |
| EP-0502060-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007087-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1991-05-30 | — | — | WO | claimed |
| US-20190255503-A1 | SILANE MIXTURES | AFFYMETRIX, INC. | 2019-08-22 | — | — | US | disclosed |
| US-20170136435-A1 | Silane Mixtures | AFFYMETRIX, INC. | 2017-05-18 | — | — | US | disclosed |
| US-9556360-B2 | Silane mixtures | AFFYMETRIX, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | INVASC THERAPEUTICS, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20120094872-A1 | SILANE MIXTURES | AFFYMETRIX, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-8105821-B2 | Silane mixtures | AFFYMETRIX, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-7659050-B2 | High resolution silicon-containing resist | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-02-09 | — | — | US | disclosed |
| WO-1993022680-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF OLIGONUCLEOTIDES AND OTHER BIOLOGICAL POLYMERS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-11-11 | — | — | WO | disclosed |
| US-5252743-A | Using cage binding compound | AFFYMAX TECHNOLOGIES N.V. (NL) | 1993-10-12 | — | — | US | disclosed |
| EP-0562025-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-09-29 | — | — | EP | disclosed |
| EP-0502060-A4 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0502060-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-09 | — | — | EP | disclosed |
| WO-1992010092-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-06-25 | — | — | WO | disclosed |
| WO-1991007087-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | REN, PCSK9, COMT | MAPT 701/4885MEN1 2495/4885KMT2A 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.