Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | SCN1A | P35498 | 1/20 | 0.66 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.66 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064827 | 0.90 | ALDH1A1 (0.73) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL15607734 | 0.86 | ALDH1A1 (0.77) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL946820 | 0.86 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL947523 | 0.85 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL76052 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL7635194 | 0.84 | PARP10 (0.51) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL9929828 | 0.83 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL3029440 | 0.83 | MAPT (0.60) | ALDH1A1LMNAMAPTGAANPC1 | |
| SCHEMBL18542252 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTSCN1ASCN2A | |
| SCHEMBL18682427 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTSCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |