Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228387 | 0.82 | MEN1 (0.58) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11226201 | 0.77 | HSD17B10 (0.49) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Lactic Acid SCHEMBL11226196 | 0.75 | HSD17B10 (0.68) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10886126 | 0.70 | TLR8 (0.38) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10885463 | 0.70 | TLR8 (0.37) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20856778 | 0.67 | KMT2A (0.59) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Lactic Acid SCHEMBL11262321 | 0.65 | KDM4E (0.66) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Ethacridine SCHEMBL31197660 | 0.65 | MEN1 (1.00) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Ethacridine SCHEMBL30775016 | 0.65 | MEN1 (1.00) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Ethacridine SCHEMBL30006678 | 0.65 | MEN1 (1.00) | MEN1KMT2AHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060491-B1 | PROTEIN PP16, PROCESS FOR CONCENTRATING AND ISOLATING IT, AND ITS USE | BEHRINGWERKE Aktiengesellschaft (DE) | 1985-06-12 | — | — | EP | disclosed |