Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355586 | 0.86 | KDM4E (0.43) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL138155 | 0.81 | MAPT (0.58) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| Water SCHEMBL6900162 | 0.81 | MAPT (0.57) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11047770 | 0.77 | MEN1 (0.47) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| Lactic Acid SCHEMBL11226196 | 0.76 | HSD17B10 (0.68) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11608363 | 0.73 | MEN1 (0.63) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11431835 | 0.69 | MEN1 (0.53) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL20856778 | 0.67 | KMT2A (0.59) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| Ethacridine SCHEMBL30775016 | 0.66 | MEN1 (1.00) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| Ethacridine SCHEMBL30006678 | 0.66 | MEN1 (1.00) | HSD17B10KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348316-A | IMMUNOSUPPRESSIVE AGENT | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |