Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | POLB | P06746 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | APEX1 | P27695 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040791 | 0.93 | NR1I2 (0.40) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10937425 | 0.89 | NR1I2 (0.43) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11046838 | 0.88 | NR1I2 (0.30) | NR1I2PGR | |
| SCHEMBL9658255 | 0.84 | NR1I2 (0.36) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11008934 | 0.84 | NR1I2 (0.44) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10643012 | 0.83 | TDP1 (0.32) | TDP1APEX1APAF1LMNATSHR | |
| SCHEMBL11038328 | 0.83 | TDP1 (0.32) | NR1I2TDP1APEX1APAF1LMNA | |
| SCHEMBL10854213 | 0.82 | NR1I2 (0.35) | NR1I2PGRTDP1HSD17B10APEX1 | |
| SCHEMBL10939452 | 0.82 | NR1I2 (0.46) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10847932 | 0.82 | KCNH2 (0.36) | NR1I2PGRMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |