Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836398 | 0.80 | TLR8 (0.55) | CYP1A2KDM4EKMT2AMEN1PDGFRB | |
| SCHEMBL4619366 | 0.79 | KDM1A (0.58) | CYP1A2KDM4EKMT2ATSHRMAPK1 | |
| SCHEMBL29742392 | 0.79 | KDM1A (0.58) | CYP1A2KDM4EKMT2ATSHRMAPK1 | |
| SCHEMBL4620228 | 0.79 | KDM1A (0.58) | CYP1A2KDM4EKMT2ATSHRMAPK1 | |
| SCHEMBL18260414 | 0.76 | TLR8 (0.58) | CYP1A2KDM4EKMT2ATSHRPDGFRB | |
| SCHEMBL18260416 | 0.76 | TLR8 (0.58) | CYP1A2KDM4EKMT2ATSHRPDGFRB | |
| SCHEMBL272613 | 0.74 | PDGFRB (0.51) | CYP1A2KDM4EKMT2APDGFRBPDGFRA | |
| SCHEMBL13302131 | 0.74 | RAB9A (0.55) | CYP1A2KDM4EKMT2ATSHRMAPK1 | |
| SCHEMBL28286268 | 0.74 | PDGFRB (0.51) | CYP1A2KDM4EKMT2APDGFRBPDGFRA | |
| SCHEMBL28284739 | 0.74 | PDGFRB (0.51) | CYP1A2KDM4EKMT2APDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474963-A | PHASE TRANSFER CATALYSTS | W. R. GRACE & CO. (US) | 1984-10-02 | — | — | US | disclosed |