Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054923 | 0.80 | AR (0.37) | ALDH1A1KDM4EARTAAR1NPC1 | |
| SCHEMBL6972728 | 0.79 | ALDH1A1 (0.42) | ALDH1A1ARTAAR1P2RX7HTR2C | |
| SCHEMBL11047730 | 0.79 | TAAR1 (0.36) | ALDH1A1KDM4ETAAR1L3MBTL1 | |
| SCHEMBL2104755 | 0.79 | HTR2C (0.42) | KDM4EARTAAR1DAOHTR2C | |
| SCHEMBL2103781 | 0.79 | TAAR1 (0.41) | ALDH1A1TAAR1IDO1 | |
| SCHEMBL2100719 | 0.78 | TAAR1 (0.40) | ARTAAR1FFAR1GPR84 | |
| SCHEMBL2103787 | 0.76 | DPP4 (0.43) | ALDH1A1 | |
| SCHEMBL11049042 | 0.75 | HTR2C (0.46) | ALDH1A1ARTAAR1HTR2CL3MBTL1 | |
| SCHEMBL27164548 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EHTR2CFFAR1POLB | |
| Hydrochloric Acid SCHEMBL23301427 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | claimed |
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |