Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327450 | 0.85 | SNCA (0.81) | SNCAPOLBHPGDCYP1A2CYP3A4 | |
| SCHEMBL29537463 | 0.85 | SNCA (0.81) | SNCAPOLBHPGDCYP1A2CYP3A4 | |
| SCHEMBL10006565 | 0.83 | SNCA (0.56) | SNCAPOLBHPGDCYP1A2CYP3A4 | |
| SCHEMBL10006568 | 0.83 | SNCA (0.56) | SNCAPOLBHPGDCYP1A2CYP3A4 | |
| SCHEMBL5429856 | 0.82 | SNCA (0.62) | SNCAMEN1KMT2APOLBHPGD | |
| SCHEMBL18046509 | 0.82 | SNCA (0.62) | SNCAMEN1KMT2APOLBHPGD | |
| SCHEMBL11048448 | 0.82 | SNCA (0.59) | SNCAMEN1KMT2APOLBHPGD | |
| SCHEMBL11048449 | 0.82 | SNCA (0.55) | SNCAMEN1KMT2APOLBHPGD | |
| SCHEMBL29954708 | 0.81 | SNCA (0.61) | SNCAMEN1KMT2APOLBHPGD | |
| SCHEMBL18046820 | 0.80 | SNCA (0.64) | SNCAMEN1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477387-A | ANTILTUMOR AGENTS | OTSUKA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0055300-A1 | PLATINUM (II) COMPLEXES AND ANTINEOPLASTIC AGENTS CONTAINING SAME AS EFFECTIVE INGREDIENTS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 1982-07-07 | — | — | EP | disclosed |