Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048448 | 0.95 | SNCA (0.59) | SNCAKMT2ALMNAMEN1CACNA1B | |
| SCHEMBL11048445 | 0.82 | SNCA (0.65) | SNCAKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10006568 | 0.81 | SNCA (0.56) | SNCAPOLBHPGDMAPT | |
| SCHEMBL10006565 | 0.81 | SNCA (0.56) | SNCAPOLBHPGDMAPT | |
| SCHEMBL28327450 | 0.80 | SNCA (0.81) | SNCAHDAC1NPC1RAB9APOLB | |
| SCHEMBL29537463 | 0.80 | SNCA (0.81) | SNCAHDAC1NPC1RAB9APOLB | |
| SCHEMBL11145664 | 0.77 | SIGMAR1 (0.46) | SNCA | |
| SCHEMBL27696783 | 0.72 | SNCA (0.77) | SNCAHDAC1NPC1RAB9A | |
| SCHEMBL11038552 | 0.72 | SNCA (0.64) | SNCAKMT2AMEN1HDAC1NPC1 | |
| SCHEMBL11038549 | 0.72 | SNCA (0.64) | SNCAKMT2AMEN1HDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477387-A | ANTILTUMOR AGENTS | OTSUKA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0055300-A1 | PLATINUM (II) COMPLEXES AND ANTINEOPLASTIC AGENTS CONTAINING SAME AS EFFECTIVE INGREDIENTS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 1982-07-07 | — | — | EP | disclosed |