SCHEMBL11048573

SCHEMBL11048573

C=CCOC(=O)c1ccc(C(=O)OCC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
CYP3A4 P08684 2/20 0.59
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
MAOA P21397 1/20 0.59
SNCA P37840 1/20 0.58
HPGD P15428 4/20 0.53
HTT P42858 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
MAPT P10636 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175786 0.90 SNCA (0.67) CA1CA2CA12CA7CA9
SCHEMBL26046537 0.89 CA12 (0.56) CA1CA2CA12CA7CA9
SCHEMBL9270334 0.89 SNCA (0.58) CA1CA2CA12CA7CA9
SCHEMBL18593579 0.89 CA12 (0.53) CA1CA2CA12CA7CA9
SCHEMBL12228311 0.87 SNCA (0.56) CA1CA2CA12CA7CA9
SCHEMBL20762833 0.86 CYP3A4 (0.53) CA1CA2CA12CA7CA9
SCHEMBL1515794 0.86 MAPT (0.59) CA1CA2CA12CA7CA9
SCHEMBL10072072 0.86 CYP3A4 (0.57) CA1CA2CA12CA7CA9
SCHEMBL2705494 0.85 SNCA (0.58) CA1CA2CA12CA7CA9
SCHEMBL8839061 0.85 SNCA (0.58) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473702-A CATALYTIC ESTER INTERCHANGE BETWEEN DIALKYL ESTER OF DICARBOXYLIC ACID AND ALLYL ALCOHOL KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-09-25 US disclosed
EP-0029362-B1 PRODUCTION OF A DIALLYL ESTER OF AN AROMATIC DICARBOXYLIC ACID KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-09-07 EP disclosed
EP-0029362-A1 Production of a diallyl ester of an aromatic dicarboxylic acid KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-05-27 EP disclosed