SCHEMBL10072072

SCHEMBL10072072

C=CCOC(=O)c1ccc(C(=O)OCC)cc1C(=O)OCC=C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.57
CA12 O43570 5/20 0.50
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
CA7 P43166 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 5/20 0.50
TSHR P16473 3/20 0.49
ALDH1A1 P00352 5/20 0.48
MAPK1 P28482 1/20 0.48
HSD17B10 Q99714 2/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
SNCA P37840 1/20 0.46
HSD17B2 P37059 1/20 0.46
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
MAOA P21397 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48751 0.92 CYP3A4 (0.66) CYP3A4CA12CA1CA2CA7
SCHEMBL29376657 0.92 CYP3A4 (0.66) CYP3A4CA12CA1CA2CA7
SCHEMBL10072249 0.88 CYP3A4 (0.57) CYP3A4TSHRALDH1A1MAPK1HSD17B10
SCHEMBL29843135 0.87 CA12 (0.62) CYP3A4CA12CA1CA2CA7
SCHEMBL321387 0.87 CA12 (0.62) CYP3A4CA12CA1CA2CA7
Benzene SCHEMBL9554798 0.87 CYP3A4 (0.63) CYP3A4CA1CA2TSHRALDH1A1
Acrylic Acid SCHEMBL2215810 0.87 CYP3A4 (0.58) CYP3A4TSHRALDH1A1MAPK1HSD17B10
SCHEMBL9247117 0.86 CYP3A4 (0.57) CYP3A4CA12CA1CA2CA7
SCHEMBL11048573 0.86 CA1 (0.61) CYP3A4CA12CA1CA2CA7
SCHEMBL18593579 0.85 CA12 (0.53) CYP3A4CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452993-A2 Thermosetting fluoropolyether adhesive composition and adhesion method Shin-Etsu Chemical Co., Ltd. (JP) 2012-05-16 EP disclosed