Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055726 | 0.91 | POLB (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL28312403 | 0.70 | ALDH1A1 (0.40) | ALDH1A1GAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11053533 | 0.66 | ALDH1A1 (0.49) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3920542 | 0.64 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AMEN1CYP1A2 | |
| SCHEMBL11145541 | 0.63 | NPC1 (0.54) | ALDH1A1CYP2C19SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL11048670 | 0.63 | SMN1; SMN2 (0.47) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14119792 | 0.62 | ALDH1A1 (0.82) | ALDH1A1GAAKMT2AMEN1GLA | |
| SCHEMBL22323277 | 0.61 | BUB1 (0.53) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL15423956 | 0.61 | ALDH1A1 (0.67) | ALDH1A1GAAKMT2AMEN1GLA | |
| SCHEMBL9751437 | 0.59 | ALDH1A1 (0.46) | ALDH1A1GAACYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431659-A | 1-(Aryl)thiocarbamoyl-2-(aryl)-3-pyrazolidinones and their nematicidal use | FMC CORPORATION (US) | 1984-02-14 | — | — | US | claimed |