Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048592 | 1.00 | ACE (0.70) | ACE | |
| SCHEMBL3725197 | 0.89 | ACE (0.67) | ACE | |
| SCHEMBL22428350 | 0.89 | ACE (0.55) | ACE | |
| SCHEMBL11180967 | 0.86 | ACE (0.71) | ACE | |
| SCHEMBL10597766 | 0.86 | ACE (0.70) | ACE | |
| SCHEMBL5160420 | 0.86 | ACE (0.70) | ACE | |
| SCHEMBL5564103 | 0.85 | KDM4E (0.68) | ACE | |
| SCHEMBL5564100 | 0.85 | KDM4E (0.68) | ACE | |
| SCHEMBL8518559 | 0.84 | NOTUM (0.67) | — | |
| SCHEMBL14002986 | 0.84 | NOTUM (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454291-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-06-12 | — | — | US | claimed |
| US-4454291-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4454292-A | CHEMICAL INTERMEDIATES OF ANGIOTENSIN CONVERTING ENZYNE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4350633-A | ENZYME INHIBITORS, HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |