Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597766 | 1.00 | ACE (0.70) | ACE | |
| SCHEMBL11048592 | 0.86 | ACE (0.70) | ACE | |
| SCHEMBL11048599 | 0.86 | ACE (0.70) | ACE | |
| SCHEMBL3725197 | 0.83 | ACE (0.67) | ACE | |
| SCHEMBL7273177 | 0.82 | ACE (1.00) | ACE | |
| SCHEMBL10924514 | 0.82 | ACE (1.00) | ACE | |
| SCHEMBL10921959 | 0.82 | ACE (1.00) | ACE | |
| SCHEMBL10920529 | 0.82 | ACE (1.00) | ACE | |
| SCHEMBL6054144 | 0.82 | ACE (1.00) | ACE | |
| SCHEMBL7356189 | 0.82 | ACE (1.00) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208607-B1 | Process for synthesis of perindopril and pharmaceutically acceptable salts thereof | LES LABORATOIRES SERVIER (FR) | 2007-04-24 | — | — | US | disclosed |
| US-20070083052-A1 | PROCESS FOR SYNTHESIS OF PERINDOPRIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF. | LES LABORATOIRES SERVIER (FR) | 2007-04-12 | — | — | US | disclosed |
| EP-1420028-B1 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | SERVIER LAB (FR) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005054276-A1 | METHOD FOR SYNTHESIS OF PERINDOPRIL AND THE PHARMACEUTICALLY-ACCEPTABLE SALTS THEREOF | LES LABORATOIRES SERVIER (FR) | 2005-06-16 | — | — | WO | disclosed |
| EP-1420028-A2 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | LES LABORATOIRES SERVIER (FR) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070083052-A1 | PROCESS FOR SYNTHESIS OF PERINDOPRIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF. | ACE, REN, QDPR | ACE 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.