Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.71 |
| ▸ | DRD3 | P35462 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | CNR2 | P34972 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052244 | 0.91 | DRD2 (0.67) | DRD2DRD3MEN1CNR1CNR2 | |
| SCHEMBL6774180 | 0.86 | DRD2 (0.71) | DRD2DRD3MEN1KMT2AHTT | |
| SCHEMBL11047821 | 0.85 | MAPT (0.62) | DRD2DRD3MEN1KMT2AGAA | |
| SCHEMBL10401425 | 0.85 | DRD2 (0.67) | DRD2DRD3MEN1CNR1CNR2 | |
| SCHEMBL16463565 | 0.83 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL1193035 | 0.83 | DRD2 (0.68) | DRD2DRD3MEN1KMT2AHTT | |
| SCHEMBL314986 | 0.83 | DRD2 (0.83) | DRD2DRD3LMNA | |
| SCHEMBL1193570 | 0.82 | DRD2 (0.60) | DRD2DRD3MEN1CNR1CNR2 | |
| SCHEMBL6771493 | 0.82 | DRD2 (0.67) | DRD2DRD3MEN1KMT2AGAA | |
| SCHEMBL10401771 | 0.82 | DRD2 (0.60) | DRD2DRD3MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446133-A | ANTIARTHRITIC AGENTS | Misuitoatsu Chemicals, Inc. (JP) | 1984-05-01 | — | — | US | disclosed |