Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA5A | P35218 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031499 | 0.87 | CYP2D6 (0.76) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5025266 | 0.86 | CYP2D6 (1.00) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL67779 | 0.84 | CYP2D6 (0.72) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29443248 | 0.84 | CYP2D6 (0.72) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15984893 | 0.83 | KDM4E (0.71) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| Phosphine SCHEMBL17375055 | 0.83 | CYP2D6 (0.70) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9387319 | 0.82 | CYP2D6 (0.74) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9797535 | 0.82 | CYP2D6 (0.68) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29975674 | 0.82 | CYP2D6 (0.68) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12687891 | 0.82 | CYP2D6 (0.68) | CYP2D6KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153828-B2 | Optical molecular sensors for cytochrome P450 activity | Life Technologies Corporation (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153828-B2 | Optical molecular sensors for cytochrome P450 activity | Life Technologies Corporation (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100105095-A1 | Optical Molecular Sensors for Cytochrome P450 Activity | Life Technologies Corporation (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100105095-A1 | Optical Molecular Sensors for Cytochrome P450 Activity | Life Technologies Corporation (US) | 2010-04-29 | — | — | US | disclosed |
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | INVITROGEN CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | INVITROGEN CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| US-20070072256-A1 | OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY | INVITROGEN CORPORATION | 2007-03-29 | — | — | US | disclosed |
| US-20070072256-A1 | OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY | INVITROGEN CORPORATION | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105095-A1 | Optical Molecular Sensors for Cytochrome P450 Activity | CYP2J2, CYP1A2, CYP2B6 | CYP2D6 5/4885KDM4E 1411/4885ALDH1A1 766/4885 |
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | CYP2J2, CYP1A2, CYP2B6 | CYP2D6 5/4885KDM4E 1411/4885ALDH1A1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.