SCHEMBL67779

SCHEMBL67779

COc1ccc2c(CBr)cc(=O)oc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.72
KDM4E B2RXH2 7/20 0.68
LCK P06239 1/20 0.68
ALDH1A1 P00352 6/20 0.67
HPGD P15428 3/20 0.67
CYP19A1 P11511 3/20 0.65
HSD17B10 Q99714 2/20 0.63
LMNA P02545 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA3 P07451 1/20 0.57
CA4 P22748 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
DYRK1A Q13627 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443248 1.00 CYP2D6 (0.72) CYP2D6KDM4ELCKALDH1A1HPGD
Phosphine SCHEMBL17375055 0.98 CYP2D6 (0.70) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL29975674 0.88 CYP2D6 (0.68) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL9797535 0.88 CYP2D6 (0.68) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL8707352 0.88 DYRK1A (0.74) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL6031499 0.88 CYP2D6 (0.76) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL9387319 0.86 CYP2D6 (0.74) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL24025689 0.85 CYP2D6 (0.72) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL17299899 0.85 CYP2D6 (0.72) CYP2D6KDM4ELCKALDH1A1HPGD
SCHEMBL18921190 0.85 CYP2D6 (0.72) CYP2D6KDM4ELCKALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4482914-A1 REAGENTS FOR FLUORESCENT, UV, AND MS LABELING OF O-GLYCANS, AND METHODS OF MAKING AND USING THEM Agilent Technologies, Inc. (US) 2025-01-01 EP claimed
CN-118871547-A Reagents for fluorescent, UV and MS labeling of O-glycans and methods of making and using the same 安捷伦科技有限公司 2024-10-29 CN claimed
CN-118084877-A Water-soluble fluorescent probe for detecting hypochlorite, and preparation method and application thereof 绵阳师范学院 2024-05-28 CN claimed
WO-2023164193-A1 REAGENTS FOR FLUORESCENT, UV, AND MS LABELING OF O-GLYCANS, AND METHODS OF MAKING AND USING THEM AGILENT TECHNOLOGIES, INC. (US) 2023-08-31 WO claimed
CN-116076422-A Early male and female identification method for stone-head fishes 浙江省海洋水产研究所 2023-05-09 CN claimed
CN-114315733-A Photoinduced cell covalent labeling fluorescent molecule, preparation method and application thereof 中国科学院上海药物研究所 2022-04-12 CN claimed
EP-0413152-B1 7-Hydroxy coumarins having substitutions in the 4 position ABBOTT LAB (US) 1996-01-10 EP claimed
US-5247099-A Process for synthesis of 7-hydroxy coumarins having substitutions in the 4-position ABBOTT LABORATORIES (US) 1993-09-21 US claimed
EP-0413152-A1 7-Hydroxy coumarins having substitutions in the 4 position ABBOTT LABORATORIES (US) 1991-02-20 EP claimed
JP-5034327-A None JP disclosed
JP-3118375-A None JP disclosed
JP-55147347-A None JP disclosed
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound FUJIFILM CORPORATION (JP) 2026-05-26 US disclosed
EP-4610657-A1 DIAGNOSIS OF IMMUNE-MEDIATED INFLAMMATORY DISEASES USING MMP12 AS INDICATOR, AND MEDICINE FOR TREATING IMMUNE-MEDIATED INFLAMMATORY DISEASES VIA MMP12 INHIBITION Keio University (JP) 2025-09-03 EP disclosed
EP-0124103-A2 Fluorometric assay of chymopapain and reagents therefor BioWhittaker, Inc. (US) 1984-11-07 EP disclosed
EP-0013910-B1 THEOPHYLLINE ANTIGENES AND ANTIBODIES, PROCESS FOR THEIR PREPARATION, THEIR USE IN THE DETERMINATION OF THEOPHYLLINE; TEST KIT AND ANTISERUM FOR THIS USE Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1982-12-08 EP disclosed
US-4302438-A Antigen, antiserum and immunoassay for theophylline BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1981-11-24 US disclosed
JP-S55147347-A PROCESS FOR ANALYZING BILE ACID JAPAN SPECTROSCOPIC CO 1980-11-17 JP disclosed
US-4231750-A Methods for performing chemical assays using fluorescence and photon counting DIAGNOSTIC REAGENTS, INC. (US) 1980-11-04 US disclosed
EP-0013910-A1 Theophylline antigenes and antibodies, process for their preparation, their use in the determination of theophylline; test kit and antiserum for this use Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1980-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound HRH1, HRH4, CUTA CYP2D6 652/4885KDM4E 2626/4885LCK 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.