Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153030 | 0.77 | CSNK2A1 (0.40) | KDM4EPDE3BPDE3ARXFP1NEK1 | |
| SCHEMBL4159917 | 0.76 | DYRK1A (0.47) | — | |
| SCHEMBL4157683 | 0.75 | PIM1 (0.37) | KDM4EPDE3BPDE3ARXFP1PIM1 | |
| SCHEMBL4156006 | 0.75 | CCNA2 (0.35) | MAP4K1KDM4EPDE3BPDE3APIM1 | |
| SCHEMBL4154216 | 0.74 | SHMT2 (0.38) | KDM4EPDE3BPDE3ARXFP1PIM1 | |
| SCHEMBL4156018 | 0.74 | HTR2C (0.51) | KDM4EPIM1PIM3PIM2LMNA | |
| SCHEMBL4157599 | 0.73 | IDH1 (0.35) | KDM4EPDE3BPDE3ARXFP1PIM1 | |
| SCHEMBL10967371 | 0.72 | PIM1 (0.38) | KDM4ERXFP1PIM1PIM3PIM2 | |
| SCHEMBL4160720 | 0.72 | HTR2C (0.46) | KDM4ELMNAHPGD | |
| SCHEMBL4163224 | 0.71 | NPC1 (0.41) | CRHBPCRHR2KDM4ERXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |