Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170140 | 0.81 | MAPK1 (0.57) | SMN1; SMN2HPGDTSHRUSP2POLB | |
| SCHEMBL29455598 | 0.81 | MAPK1 (0.57) | SMN1; SMN2HPGDTSHRUSP2POLB | |
| Hydrochloric Acid SCHEMBL29709689 | 0.79 | MAPK1 (0.55) | SMN1; SMN2HPGDTSHRUSP2POLB | |
| SCHEMBL105029 | 0.78 | NPC1 (0.54) | MAPTSMN1; SMN2HPGDHSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL28837681 | 0.76 | NPC1 (0.52) | MAPTSMN1; SMN2HPGDHSD17B10MEN1 | |
| SCHEMBL11221096 | 0.76 | NPC1 (0.52) | MAPTSMN1; SMN2HPGDHSD17B10MEN1 | |
| Water SCHEMBL28205057 | 0.76 | PSMB8 (0.53) | MAPTSMN1; SMN2HPGDHSD17B10MEN1 | |
| SCHEMBL10670777 | 0.76 | NPC1 (0.52) | MAPTSMN1; SMN2HPGDHSD17B10MEN1 | |
| SCHEMBL11044195 | 0.74 | NPC1 (0.50) | MAPTSMN1; SMN2HPGDHSD17B10MEN1 | |
| Formic Acid SCHEMBL28868401 | 0.72 | MAPT (0.48) | MAPTSMN1; SMN2HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153656-A1 | Method for the preparation of 2,6-dichlorobenzoxazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-04 | — | — | EP | disclosed |