Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114298 | 0.84 | KMT2A (0.56) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL11069090 | 0.83 | KMT2A (0.59) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL11046091 | 0.82 | KMT2A (0.57) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL10599395 | 0.81 | KMT2A (0.59) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL9004930 | 0.81 | KMT2A (0.59) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL9004966 | 0.81 | KMT2A (0.59) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL10599398 | 0.81 | KMT2A (0.59) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL22439708 | 0.78 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL9862437 | 0.78 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT | |
| SCHEMBL10705868 | 0.78 | KMT2A (0.59) | KMT2ACYP3A4ALDH1A1HSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117578-A2 | Azole-substituted alcohol derivatives | SHIONOGI & CO., LTD. (JP) | 1984-09-05 | — | — | EP | disclosed |