Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046091 | 0.85 | KMT2A (0.57) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL11190014 | 0.85 | KMT2A (0.56) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL11114298 | 0.84 | KMT2A (0.56) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL11049367 | 0.83 | KMT2A (0.55) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL11071704 | 0.82 | LMNA (0.50) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL22439708 | 0.81 | KMT2A (0.53) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL10705868 | 0.81 | KMT2A (0.59) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL7809405 | 0.81 | KMT2A (0.52) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL11046029 | 0.80 | KMT2A (0.52) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT | |
| SCHEMBL9788457 | 0.80 | KMT2A (0.52) | KMT2AHSP90AA1CYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099165-A1 | Triazole and imidazole compounds, process for their preparation and their use as fungicides and plant growth regulators, and intermediates for their synthesis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-25 | — | — | EP | disclosed |