Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109535 | 0.95 | ALDH1A1 (0.66) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL16908424 | 0.91 | ALDH1A1 (0.59) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL109196 | 0.89 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL109610 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5557905 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4EHPGDPAOXAPEX1 | |
| SCHEMBL109864 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4EHPGDPAOXAPEX1 | |
| SCHEMBL21610956 | 0.80 | APEX1 (0.49) | ALDH1A1KDM4ESMN1; SMN2LMNAAPEX1 | |
| SCHEMBL109564 | 0.80 | ALDH1A1 (0.65) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11070508 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EHPGDPAOXAPEX1 | |
| SCHEMBL159564 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2APEX1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100719-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |