SCHEMBL11049650

SCHEMBL11049650

C=C(C)C(=O)OCO[Si](CCC)(OC)OC.[SiH4]

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
THRB P10828 1/20 0.39
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59695 0.98 TSHR (0.42) TSHRTHRBALDH1A1
SCHEMBL2470350 0.94 ALDH1A1 (0.46) TSHRTHRBALDH1A1
SCHEMBL27680542 0.89 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL27660519 0.88 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL29154616 0.86 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL16754226 0.86 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL29154618 0.86 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL27871186 0.86 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL26648800 0.86 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL27710015 0.86 TSHR (0.53) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103665729-B Oil-extended styrene-butadiene rubber containing nano silicon dioxide on surface, composition and preparation method thereof PETROCHINA COMPANY LIMITED (CN) 2016-05-11 CN disclosed
US-4443197-A ANTICARIES, DRILLING, ACID ETCHING, FILLING KURARAY CO., LTD. (JP) 1984-04-17 US disclosed