Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29985472 | 0.89 | NPC1 (0.54) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL93505 | 0.89 | NPC1 (0.54) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL5459312 | 0.87 | GAA (0.50) | ALDH1A1TSHRGAACA12CA1 | |
| SCHEMBL5390124 | 0.87 | GAA (0.53) | ALDH1A1TSHRGAACA12CA1 | |
| SCHEMBL8151695 | 0.86 | MAOB (0.60) | ALDH1A1PTPN1MAOBMAPTHPGD | |
| SCHEMBL3296021 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRGAACA12CA1 | |
| SCHEMBL93400 | 0.84 | HPGD (0.61) | ALDH1A1GAAPTPN1SLC5A1SLC5A2 | |
| SCHEMBL29644609 | 0.84 | HPGD (0.61) | ALDH1A1GAAPTPN1SLC5A1SLC5A2 | |
| SCHEMBL3953525 | 0.83 | CA12 (0.57) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL31364105 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028063-B1 | PHENOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-06-13 | — | — | EP | disclosed |
| EP-0028063-A1 | Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-05-06 | — | — | EP | disclosed |