Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891651 | 0.91 | PGR (0.62) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10889253 | 0.90 | PGR (0.72) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10892048 | 0.90 | PGR (0.65) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10892757 | 0.90 | PGR (0.65) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10893865 | 0.89 | PGR (0.64) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10894899 | 0.88 | PGR (0.63) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10897948 | 0.87 | PGR (0.62) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11118245 | 0.87 | PGR (0.62) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10893984 | 0.87 | PGR (0.59) | PGRSERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10894511 | 0.86 | PGR (0.57) | PGRSERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462996-A | WITH NONIONIC SURFACTANT AND P-HYDROXYBENZOIC ACID ESTER; ANTIANDROGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| US-3953483-A | ANTI-ANDROGENIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-27 | — | — | US | disclosed |