Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049628 | 0.91 | SLC29A1 (0.43) | GBA1SLC29A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11045301 | 0.89 | GBA1 (0.41) | GBA1SLC29A1MAPTSMN1; SMN2PDE4A | |
| SCHEMBL11028181 | 0.89 | SLC29A1 (0.43) | GBA1SLC29A1PDE4APDE4BPDE4C | |
| SCHEMBL11032824 | 0.89 | SLC29A1 (0.43) | SLC29A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL2460092 | 0.89 | SLC29A1 (0.45) | GBA1SLC29A1ALDH1A1HPGDPDE4A | |
| SCHEMBL11031003 | 0.88 | GBA1 (0.41) | GBA1SLC29A1CCNE2CCNE1CDK2 | |
| SCHEMBL11048512 | 0.85 | SLC29A1 (0.41) | GBA1SLC29A1ALDH1A1SMN1; SMN2PDE4A | |
| SCHEMBL11045049 | 0.84 | CCNE2 (0.51) | GBA1SLC29A1CCNE2CCNE1CDK2 | |
| SCHEMBL10666008 | 0.84 | SLC29A1 (0.42) | SLC29A1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11046570 | 0.83 | CYP1A2 (0.40) | SLC29A1CDK2ALDH1A1HPGDPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |