Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103783 | 0.78 | TAAR1 (0.46) | NOS2NOS3HTR1D | |
| SCHEMBL10405991 | 0.76 | — | — | |
| SCHEMBL20152921 | 0.75 | HTR1D (0.35) | HTR1DHTR1B | |
| SCHEMBL2102413 | 0.75 | — | — | |
| SCHEMBL2103250 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL7249546 | 0.73 | HPGD (0.33) | — | |
| SCHEMBL9645373 | 0.72 | NNMT (0.32) | — | |
| SCHEMBL10406697 | 0.71 | HTR1D (0.41) | HTR1DHTR1B | |
| SCHEMBL4629510 | 0.71 | TAAR1 (0.40) | HTR1D | |
| SCHEMBL2102247 | 0.71 | TAAR1 (0.41) | NOS2NOS3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | claimed |
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |