Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | SLC8A1 | P32418 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12556374 | 0.88 | ESR1 (0.55) | ESR1ESR2MAOBSLC8A1 | |
| SCHEMBL25294651 | 0.81 | ESR1 (0.55) | ESR1ESR2SLC8A1 | |
| SCHEMBL11053787 | 0.81 | ESR1 (0.59) | ESR1ESR2SLC8A1 | |
| SCHEMBL4361595 | 0.81 | ESR2 (0.82) | ESR1ESR2MAOBSLC8A1 | |
| SCHEMBL11047059 | 0.81 | MAOB (0.55) | ESR1ESR2MAOB | |
| SCHEMBL11053487 | 0.81 | ABCB1 (0.61) | ESR1ESR2MAOBSLC8A1 | |
| SCHEMBL14144587 | 0.81 | ESR1 (0.48) | ESR1ESR2MAOBSLC8A1 | |
| Flavane SCHEMBL14394530 | 0.80 | ESR1 (0.51) | ESR1ESR2MAOBSLC8A1 | |
| Flavane SCHEMBL29478071 | 0.80 | ESR1 (0.51) | ESR1ESR2MAOBSLC8A1 | |
| Flavane SCHEMBL123287 | 0.80 | ESR1 (0.51) | ESR1ESR2MAOBSLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461907-A | Amino-substituted flavans useful as anti-viral agents | BURROUGHS WELLCOME CO. | 1984-07-24 | — | — | US | disclosed |