Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SLC8A1 | P32418 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavane SCHEMBL27595228 | 1.00 | ESR1 (0.51) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL27889134 | 1.00 | ESR1 (0.51) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL29478071 | 1.00 | ESR1 (0.51) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL123287 | 1.00 | ESR1 (0.51) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL28787244 | 0.98 | ESR1 (0.50) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL28405195 | 0.98 | ESR1 (0.50) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL28394714 | 0.98 | ESR1 (0.50) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL28529260 | 0.98 | ESR1 (0.50) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL28823768 | 0.98 | ESR1 (0.50) | ESR1ESR2KDM4EADORA3AR | |
| Flavane SCHEMBL26661841 | 0.98 | ESR1 (0.54) | ESR1ESR2KDM4EADORA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9980937-B2 | Therapeutic agent for Alzheimer's disease | NAGASAKI UNIVERSITY (JP) | 2018-05-29 | — | — | US | disclosed |
| US-9980937-B2 | Therapeutic agent for Alzheimer's disease | NAGASAKI UNIVERSITY (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20170252318-A1 | NOVEL THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE | NAGASAKI UNIVERSITY (JP) | 2017-09-07 | — | — | US | disclosed |
| US-20170252318-A1 | NOVEL THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE | NAGASAKI UNIVERSITY (JP) | 2017-09-07 | — | — | US | disclosed |
| EP-1317437-B1 | SYNTHESIS OF 4-ALPHA-ARYLEPICATECHINS | MARS INC (US) | 2007-10-03 | — | — | EP | disclosed |
| US-7268240-B2 | Synthetic methods for polyphenols | MARS, INC. | 2007-09-11 | — | — | US | disclosed |
| US-20070197804-A1 | Synthesis of 4alpha-arylepicatechins | MARS, INCORPORATED | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170252318-A1 | NOVEL THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE | PSEN2, BACE1, PSEN1 | ESR1 688/4885ESR2 322/4885KDM4E 3469/4885 |
| US-20070197804-A1 | Synthesis of 4alpha-arylepicatechins | FABP7, FABP4, TEAD4 | ESR1 896/4885ESR2 405/4885KDM4E 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.