Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051453 | 0.86 | MAPT (0.69) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL11054689 | 0.86 | MAPT (0.69) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL7364265 | 0.81 | MAPT (0.74) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL6576123 | 0.79 | MAPT (0.73) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL7366956 | 0.77 | IDO1 (0.62) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL14895856 | 0.77 | IDO1 (0.62) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL11168890 | 0.76 | IDO1 (0.71) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL11050192 | 0.76 | IDO1 (0.61) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL30594080 | 0.74 | IDO1 (1.00) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL11857681 | 0.74 | MAPT (0.96) | IDO1MAPTTDP1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430265-A | IMMUNOSTIMULATORY ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| US-4369178-A | Glucosamine peptide derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-18 | — | — | US | disclosed |
| EP-0015468-B1 | 6-DEOXYGLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-29 | — | — | EP | disclosed |
| US-4314998-A | 6-Deoxyglucosamine-peptide derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0014984-A1 | Glucosamine-peptide derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-09-03 | — | — | EP | disclosed |
| EP-0002677-A1 | Glucosamine-peptide derivatives and their pharmaceutical compositions | Takeda Chemical Industries, Ltd. (JP) | 1979-07-11 | — | — | EP | disclosed |