Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15695725 | 0.87 | MAPT (0.70) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL15344010 | 0.85 | MAPT (0.73) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL6576123 | 0.82 | MAPT (0.73) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL13033957 | 0.81 | MAPT (0.61) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL14895856 | 0.80 | IDO1 (0.62) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL7364265 | 0.80 | MAPT (0.74) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL7364714 | 0.79 | IDO1 (0.56) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL11050192 | 0.78 | IDO1 (0.61) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL30594080 | 0.77 | IDO1 (1.00) | IDO1MAPTTDP1ALDH1A1THRB | |
| SCHEMBL11050186 | 0.77 | IDO1 (0.59) | IDO1MAPTTDP1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | claimed |
| US-4831265-A | ANTIFIBROTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |