SCHEMBL11050264

SCHEMBL11050264

Clc1ccc2c(c1)OC(c1ccccc1)CC2

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.55
ESR2 Q92731 2/20 0.55
FFAR1 O14842 2/20 0.46
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM1A O60341 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
SLC8A1 P32418 12/20 0.42
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11215778 0.90 ESR1 (0.62) ESR1ESR2FFAR1
SCHEMBL11053787 0.88 ESR1 (0.59) ESR1ESR2ATMSMN1; SMN2SLC8A1
SCHEMBL1934071 0.81 ESR1 (0.55) ESR1ESR2FFAR1SLC8A1
SCHEMBL1933740 0.81 ESR1 (0.82) ESR1ESR2FFAR1MAOAMAOB
SCHEMBL1932818 0.81 ESR1 (0.82) ESR1ESR2FFAR1MAOAMAOB
SCHEMBL1934690 0.81 ESR1 (0.82) ESR1ESR2FFAR1MAOAMAOB
SCHEMBL1933038 0.81 ESR1 (0.55) ESR1ESR2FFAR1SLC8A1
SCHEMBL12556374 0.81 ESR1 (0.55) ESR1ESR2FFAR1MAOBSLC8A1
SCHEMBL1933040 0.81 ESR1 (0.55) ESR1ESR2FFAR1SLC8A1
SCHEMBL11048736 0.81 ESR1 (0.54) ESR1ESR2FFAR1MAOBSLC8A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126973-A Cholesterol oxidase from sporocystoid, mutant thereof, expression method thereof and application thereof in disinsection 中国农业科学院生物技术研究所 2024-06-04 CN disclosed
US-4461907-A Amino-substituted flavans useful as anti-viral agents BURROUGHS WELLCOME CO. 1984-07-24 US disclosed