Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059714 | 0.85 | TSHR (0.37) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL11059738 | 0.85 | TSHR (0.37) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL37351 | 0.80 | TSHR (0.54) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL25435787 | 0.80 | TSHR (0.54) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL11060087 | 0.79 | SMN1; SMN2 (0.32) | TSHRALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL9998248 | 0.78 | TSHR (0.52) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL11055977 | 0.78 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL11053953 | 0.77 | ALDH1A1 (0.59) | TSHRLMNACYP2C9ALDH1A1 | |
| SCHEMBL305672 | 0.74 | TSHR (0.45) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL11061767 | 0.74 | NPC1 (0.34) | TDP1MEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487781-A | HEAT RESISTANCE; PHOTOSTABILITY | SANKYO COMPANY LIMITED (JP) | 1984-12-11 | — | — | US | disclosed |