Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25178105 | 1.00 | LMNA (0.48) | LMNATSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL25185229 | 1.00 | LMNA (0.48) | LMNATSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL25171262 | 1.00 | LMNA (0.48) | LMNATSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL25182480 | 0.98 | LMNA (0.44) | LMNATSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL25182517 | 0.98 | LMNA (0.50) | LMNATSHRDNM1ALDH1A1FAAH | |
| SCHEMBL9445614 | 0.98 | LMNA (0.50) | LMNATSHRDNM1ALDH1A1FAAH | |
| SCHEMBL15687620 | 0.98 | LMNA (0.50) | LMNATSHRDNM1ALDH1A1FAAH | |
| SCHEMBL25178065 | 0.98 | LMNA (0.50) | LMNATSHRDNM1ALDH1A1FAAH | |
| SCHEMBL25181795 | 0.98 | LMNA (0.50) | LMNATSHRDNM1ALDH1A1FAAH | |
| SCHEMBL11766872 | 0.95 | LMNA (0.46) | LMNATSHRDNM1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431836-A | Hydrogenation using chitin and chitosan based immobilized metal catalysts | UOP INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4367355-A | Hydrogenation using chitin and chitosan based immobilized metal catalysts | UOP INC. (US) | 1983-01-04 | — | — | US | disclosed |