Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24593930 | 0.84 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL17860871 | 0.79 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL12562679 | 0.79 | CYP3A4 (0.58) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL17848877 | 0.78 | CYP3A4 (0.47) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL8837154 | 0.77 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL24593983 | 0.77 | CYP3A4 (0.45) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL2962705 | 0.76 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL10426582 | 0.75 | TSHR (0.48) | TSHR | |
| SCHEMBL575252 | 0.74 | CYP3A4 (0.52) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL575341 | 0.74 | CYP3A4 (0.52) | CYP3A4LPAR3LPAR1LPAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478761-A | Method for preparing fluorine-containing phosphonates | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4393011-A | Method for the preparation of fluorine-containing phosphonates and phosphonic acids | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4330486-A | Bis(phosphonic acid) difluoromethane | UNIVERSITY OF IOWA RESEACH FOUNDATION (US) | 1982-05-18 | — | — | US | disclosed |