SCHEMBL8837154

SCHEMBL8837154

CCCCOP(=O)(OCCCC)C(Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.56
LPAR3 Q9UBY5 3/20 0.43
LPAR1 Q92633 2/20 0.43
LPAR2 Q9HBW0 2/20 0.43
TSHR P16473 1/20 0.43
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbon Tetrachloride SCHEMBL28093599 0.79 CYP3A4 (0.81) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL12562679 0.79 CYP3A4 (0.58) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL16816999 0.78 CYP3A4 (0.52) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL11050434 0.77 CYP3A4 (0.56) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL2962705 0.76 CYP3A4 (0.54) CYP3A4LPAR3LPAR1LPAR2TSHR
Chloromethane SCHEMBL11360800 0.74 CYP3A4 (0.58) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL3132134 0.73
SCHEMBL178128 0.73 CYP3A4 (0.64) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL11830671 0.72 CYP3A4 (0.70) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL1020179 0.72 CYP3A4 (1.00) CYP3A4LPAR3LPAR1LPAR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599474-A SILICON OIL CARRIER FLUID, MAGNETORHEOLOGICAL PARTICLES LORD CORPORATION (US) 1997-02-04 US disclosed
US-4280916-A MOTOR OIL, ADDITIVES FOR CRANKCASE OIL CONTAINING AN ALIPHATIC CARBOXYLIC AMIDE TO REDUCE FUEL CONSUMPTION SHELL OIL COMPANY (US) 1981-07-28 US disclosed