Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | IGF1R | P08069 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673848 | 0.87 | KDM4E (1.00) | KDM4EMAPTRAB9ATRPV1POLB | |
| SCHEMBL21751022 | 0.86 | KDM4E (0.79) | KDM4EMAPTRAB9ATRPV1POLB | |
| SCHEMBL8067681 | 0.86 | KDM4E (0.60) | KDM4EMAPTRAB9ATRPV1POLB | |
| SCHEMBL8067675 | 0.86 | KDM4E (0.60) | KDM4EMAPTRAB9ATRPV1POLB | |
| SCHEMBL30393282 | 0.85 | KDM4E (0.82) | KDM4EMAPTRAB9APOLBKMT2A | |
| SCHEMBL1276481 | 0.85 | KDM4E (0.82) | KDM4EMAPTRAB9APOLBKMT2A | |
| SCHEMBL11049554 | 0.84 | MAPT (0.77) | KDM4EMAPTRAB9ATRPV1POLB | |
| SCHEMBL11052575 | 0.84 | RAB9A (1.00) | KDM4EMAPTRAB9APOLBKMT2A | |
| SCHEMBL12827103 | 0.84 | KDM4E (0.77) | KDM4EMAPTRAB9ATRPV1POLB | |
| SCHEMBL12305496 | 0.82 | POLB (0.80) | KDM4EMAPTRAB9ATRPV1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |