Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 5/20 | 0.45 |
| ▸ | CASP6 | P55212 | 3/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049799 | 0.94 | TIMP3 (0.48) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11052317 | 0.91 | TIMP3 (0.53) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11065963 | 0.90 | TIMP3 (0.48) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11055518 | 0.90 | TIMP3 (0.48) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11071013 | 0.90 | TIMP3 (0.47) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11059267 | 0.88 | APEX1 (0.54) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11063813 | 0.86 | TIMP3 (0.52) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11065104 | 0.86 | TIMP3 (0.42) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11050468 | 0.84 | TIMP3 (0.43) | TIMP3CASP6CTDSP1APEX1HSD17B10 | |
| SCHEMBL11050210 | 0.83 | APEX1 (0.56) | TIMP3CASP6CTDSP1APEX1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |