Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366348 | 0.89 | SIGMAR1 (0.60) | SIGMAR1OPRM1OPRK1 | |
| SCHEMBL10366347 | 0.89 | SIGMAR1 (0.60) | SIGMAR1OPRM1OPRK1 | |
| SCHEMBL15962423 | 0.76 | SIGMAR1 (1.00) | SIGMAR1OPRK1 | |
| SCHEMBL10888788 | 0.74 | SIGMAR1 (0.84) | SIGMAR1OPRM1OPRK1 | |
| SCHEMBL10888939 | 0.74 | SIGMAR1 (0.84) | SIGMAR1OPRM1OPRK1 | |
| SCHEMBL5142330 | 0.73 | SIGMAR1 (1.00) | SIGMAR1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL10890281 | 0.73 | SIGMAR1 (0.82) | SIGMAR1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL10890286 | 0.73 | SIGMAR1 (0.82) | SIGMAR1OPRM1OPRK1 | |
| SCHEMBL11050552 | 0.73 | SIGMAR1 (0.65) | SIGMAR1OPRM1OPRK1 | |
| SCHEMBL3524893 | 0.71 | SIGMAR1 (0.78) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147085-A2 | Substituted trans-1.2-diaminocyclohexyl amide compounds | WARNER-LAMBERT COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |