Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | APEX1 | P27695 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050575 | 1.00 | NR1I2 (0.63) | NR1I2PGRPTGS2PSMD14MMP2 | |
| SCHEMBL11047007 | 0.94 | NR1I2 (0.72) | NR1I2PGRPTGS2PSMD14MMP2 | |
| SCHEMBL11051674 | 0.91 | PTGS1 (0.59) | NR1I2PGRPTGS2PSMD14MMP2 | |
| SCHEMBL11046150 | 0.86 | NR1I2 (0.51) | NR1I2PGRPTGS2PSMD14MMP2 | |
| SCHEMBL11046153 | 0.86 | NR1I2 (0.51) | NR1I2PGRPTGS2PSMD14MMP2 | |
| SCHEMBL6665359 | 0.85 | NR1I2 (0.56) | NR1I2PGRPTGS1HTR2CABCB11 | |
| SCHEMBL8675659 | 0.85 | NR1I2 (0.56) | NR1I2PGRPTGS1HTR2CABCB11 | |
| SCHEMBL11482866 | 0.82 | NR1I2 (0.73) | NR1I2PGRPTGS2PSMD14MMP2 | |
| SCHEMBL10863015 | 0.81 | NR1I2 (0.64) | NR1I2PGRPTGS2PTGS1HTR2C | |
| SCHEMBL11039881 | 0.81 | NR1I2 (0.73) | NR1I2PGRPTGS2PSMD14MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436903-A | Process for the production of 7 β-substituted-3-unsubstituted-3-cephem-4-carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |