Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665359 | 1.00 | NR1I2 (0.56) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10863015 | 0.94 | NR1I2 (0.64) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10863010 | 0.94 | NR1I2 (0.64) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10863677 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10863684 | 0.93 | TDP1 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL8492369 | 0.90 | PTGS1 (0.52) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL13585050 | 0.88 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL13585052 | 0.88 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11050575 | 0.85 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11050577 | 0.85 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854227-A | Therapeutic derivatives of diphosphonates | ELIZANOR BIOPHARMACUETICALS, INC. | 1998-12-29 | — | — | US | disclosed |