SCHEMBL11050599

SCHEMBL11050599

Cc1ccc(S(=O)(=O)OCCCCCCCCCCCCOS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
GAA P10253 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA9 Q16790 2/20 0.46
PSMD10 O75832 1/20 0.44
STAT3 P40763 1/20 0.44
G6PD P11413 1/20 0.44
CYP24A1 Q07973 2/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
VDR P11473 1/20 0.42
TLR9 Q9NR96 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8484861 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4815560 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL3545668 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL8483813 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4812770 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4951882 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4954181 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL890725 0.98 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL483847 0.94 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19GAA
SCHEMBL4193998 0.93 RECQL (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015081284-A1 BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME COFERON, INC. (US) 2015-06-04 WO disclosed
US-4444928-A NONHYDROLYZING LIGHT STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1984-04-24 US disclosed