SCHEMBL1105071

SCHEMBL1105071

[SiH3]C1CCCc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.53
TSHR P16473 1/20 0.44
ADRA2A P08913 2/20 0.44
ADRA1A P35348 2/20 0.44
LMNA P02545 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1B P35368 1/20 0.44
HTR1A P08908 1/20 0.44
OPRM1 P35372 1/20 0.44
HTT P42858 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRNA7 P36544 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517913 0.78 IDO1 (0.53) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL12928463 0.78 IDO1 (0.53) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL15004316 0.78 IDO1 (0.53) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL29357487 0.77 IDO1 (0.57) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL145977 0.77 IDO1 (0.57) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL7898127 0.77 IDO1 (0.52) IDO1
SCHEMBL1705441 0.77 IDO1 (0.52) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL13082165 0.76 IDO1 (0.55) IDO1TSHRADRA2AADRA1ALMNA
SCHEMBL5541899 0.75 CYP19A1 (0.54)
SCHEMBL15147106 0.74 IDO1 (0.53) IDO1TSHRADRA2AADRA1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153836-B2 Silsesquioxane compound mixture, hydrolyzable silane compound, making methods, resist composition, patterning process, and substrate processing SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-10 US disclosed
US-20080311514-A1 SILSESQUIOXANE COMPOUND MIXTURE, HYDROLYZABLE SILANE COMPOUND, MAKING METHODS, RESIST COMPOSITION, PATTERNING PROCESS, AND SUBSTRATE PROCESSING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311514-A1 SILSESQUIOXANE COMPOUND MIXTURE, HYDROLYZABLE SILANE COMPOUND, MAKING METHODS, RESIST COMPOSITION, PATTERNING PROCESS, AND SUBSTRATE PROCESSING STS, LSS, SRMS IDO1 2371/4885TSHR 4804/4885ADRA2A 3804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.