SCHEMBL11050783

SCHEMBL11050783

Cc1c(CON=CC2CC2)cccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 20/20 0.48
PDCD1 Q15116 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050782 1.00 CD274 (0.48) CD274PDCD1
SCHEMBL11049259 0.76 CD274 (0.57) CD274PDCD1
SCHEMBL11056231 0.73 CD274 (0.48) CD274PDCD1
SCHEMBL11056212 0.73 CD274 (0.48) CD274PDCD1
SCHEMBL27844226 0.73 CD274 (0.67) CD274PDCD1
SCHEMBL17898328 0.72 CD274 (0.65) CD274PDCD1
SCHEMBL19227844 0.71 CD274 (0.53) CD274PDCD1
SCHEMBL19227843 0.71 CD274 (0.53) CD274PDCD1
SCHEMBL17218598 0.70 DPP4 (0.42) CD274PDCD1
SCHEMBL11057242 0.69 CD274 (0.43) CD274PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125248-A1 INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS FMC Corporation (US) 1984-11-21 EP disclosed
WO-1984001772-A1 INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS FMC CORP (US) 1984-05-10 WO disclosed