SCHEMBL11049259

SCHEMBL11049259

C=NOCc1cccc(-c2ccccc2)c1C

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 18/20 0.57
PDCD1 Q15116 1/20 0.57
EPHX1 P07099 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14074969 0.84 DPP4 (0.48) CD274PDCD1
SCHEMBL27844226 0.81 CD274 (0.67) CD274PDCD1EPHX1
SCHEMBL17898328 0.80 CD274 (0.65) CD274PDCD1EPHX1
SCHEMBL21620376 0.77 CD274 (0.53) CD274PDCD1EPHX1
SCHEMBL29271887 0.77 CD274 (0.63) CD274PDCD1
SCHEMBL11050783 0.76 CD274 (0.48) CD274PDCD1
SCHEMBL8769176 0.76 CD274 (0.51) CD274PDCD1EPHX1
SCHEMBL11050782 0.76 CD274 (0.48) CD274PDCD1
SCHEMBL5223243 0.73 TAAR1 (0.42)
SCHEMBL358303 0.73 CD274 (1.00) CD274PDCD1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125248-A1 INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS FMC Corporation (US) 1984-11-21 EP disclosed
WO-1984001772-A1 INSECTICIDAL SUBSTITUTED-BIPHENYLMETHYL OXIME ETHERS FMC CORP (US) 1984-05-10 WO disclosed