Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672873 | 0.81 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL15672889 | 0.81 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL4483031 | 0.79 | ESR1 (0.55) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL11668188 | 0.78 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL6403369 | 0.78 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL15672835 | 0.76 | ESR1 (0.59) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL11737973 | 0.75 | ESR1 (0.67) | ESR1ALOX5PTGESL3MBTL1NR1I2 | |
| SCHEMBL14234294 | 0.75 | ESR1 (0.62) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL14820 | 0.74 | ESR1 (0.60) | ESR1ALOX5PTGESL3MBTL1NR1I2 | |
| SCHEMBL3130571 | 0.74 | ESR1 (0.47) | ESR1NPC1JAK2RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461696-A | Shale-oil recovery process | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-07-24 | — | — | US | disclosed |
| US-4458757-A | In situ shale-oil recovery process | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-07-10 | — | — | US | disclosed |