Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483031 | 0.84 | ESR1 (0.55) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL6403369 | 0.83 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL15672873 | 0.83 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL15672889 | 0.83 | ESR1 (0.54) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL14234294 | 0.80 | ESR1 (0.62) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL14820 | 0.79 | ESR1 (0.60) | ESR1ALOX5PTGESNR1I2TDP1 | |
| SCHEMBL11050842 | 0.78 | ESR1 (0.49) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL7213231 | 0.77 | ESR1 (0.59) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL7213233 | 0.77 | ESR1 (0.59) | ESR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL15672835 | 0.77 | ESR1 (0.59) | ESR1NPC1JAK2RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067741-A | Hardening photographic layers containing silver halide with a 1-sulphonyl-4-amino-pyridinium salt | AGFA-GEVAERT, A.G. (DT) | 1978-01-10 | — | — | US | disclosed |