Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 2/20 | 0.38 |
| ▸ | CDA | P32320 | 2/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599205 | 0.91 | — | — | |
| SCHEMBL10512933 | 0.82 | — | — | |
| SCHEMBL21711068 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTKDM4EPOLBGAA | |
| SCHEMBL8732854 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTKDM4EPOLBGAA | |
| SCHEMBL19291821 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTKDM4EPOLBGAA | |
| SCHEMBL1446337 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL28954131 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTKDM4EPOLBGAA | |
| SCHEMBL1421683 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL8048986 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL21711067 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4488993-A | Amidinoureas | WILLIAM H. RORER, INC. | 1984-12-18 | — | — | US | disclosed |