Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809030 | 0.82 | ALDH1A1 (0.60) | MAPTMEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11060114 | 0.82 | ALDH1A1 (0.60) | MAPTMEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11718612 | 0.81 | FFAR1 (0.54) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL159434 | 0.81 | FFAR1 (0.54) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL11059512 | 0.81 | ALDH1A1 (0.58) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7851509 | 0.80 | MEN1 (0.50) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28847226 | 0.80 | FFAR1 (0.53) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10538012 | 0.80 | FFAR1 (0.53) | MAPTMEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL30605752 | 0.79 | MEN1 (0.56) | MAPTMEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL28590040 | 0.79 | MEN1 (0.56) | MAPTMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490370-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0122155-A2 | Improvements in or relating to naphthylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |